The research aims to extend the lifespan of biosensors.
Ph.D. student in the Daniel J. Epstein Department of Industrial and Systems Engineering, Weizhi Lin and her collaborators have been honored with a best paper award at the 2022 Institute of Industrial and Systems Engineers (IISE) Conference in Seattle.
The work, co-authored by ISE postdoctoral research fellow Cesar Ruiz and Professor of Industrial and Systems Engineering and Chemical Engineering and Materials Science Qiang Huang, in collaboration with Dr Hadar Ben-Yoav’s group at Ben-Gurion University, Israel, was recognized with the Quality Control and Reliability Engineering (QCRE) Track Best Paper Award at the conference.
Lin said that the paper established a data-driven model to extend the lifespan of biosensors, which are important devices used to analyze biological samples in medicine.
“Electrochemical biosensors enable a fast and accurate medicine concentration estimation in biofluid samples such as blood, Lin said. “However, the estimation accuracy decreases after every usage because of the ‘biofouling’ phenomenon. Biofouling generates attachments on the electrodes that dramatically affect the shape of the measurement signals, thus reducing the accuracy.”
Lin said that the research team’s model can predict and correct for shape changes induced by the biofouling effect.
“As a result, the concentration estimation precision deteriorates less under biofouling, allowing biosensors to have a longer service life,” Lin said.
Published on May 26th, 2022
Last updated on May 26th, 2022